B11: Rational tuning of plasma and liquid chemistry for biocatalysis
Principal Investigators: J. Bandow, J. Golda, A. Gibson
Team
Bandow, Julia (Principal Investigator) |
Golda, Judith (Principal Investigator) |
Klopsch, Sabrina (PhD) |
Schüttler, Steffen (PhD) |
Schöne, Anna Lena (PhD) |
Eichstaedt, Niklas (Master) |
Description
Plasma-driven biocatalysis seeks to use plasma-produced reactive species, such as hydrogen peroxide, as reactants for the enzymatic conversion of substrates into valuable products. A key to achieving industrial use of this approach is to produce reactants in sufficient amounts and with high energy efficiency. The aim of this project is to develop a rational scheme for tuning the plasma-biocatalysis system by combining expertise and insight from experimental plasma and liquid diagnostics, numerical plasma and liquid chemistry simulations and biotechnology. In addition to characterising rates and mechanisms of hydrogen peroxide generation, the formation of unwanted plasma species that are toxic to enzymes will be monitored under different plasma operating conditions. On the basis of simulation and experiment, new strategies will be developed to increase the biocatalytic yield.
Publications
- Production and transport of plasma-generated hydrogen peroxide from gas to liquid
Steffen Schüttler , Anna Lena Schöne , Emanuel Jeß, Andrew R. Gibson and Judith Golda
Phys. Chem. Chem. Phys., 2024, 26, 8255-8272 - Validation of in situ diagnostics for the detection of OH and H2O2 in liquids treated by a humid atmospheric pressure plasma jet
S Schüttler, L Jolmes, E Jeß, K Tschulik, J Golda
Plasma. Process Polym. 2023, e2300079 - Comparison of CO production and Escherichia coli inactivation by a kHz and a MHz plasma jet
E. Mestre, I. Orel, D. Henze, L. Chauvet, S. Burhenn, S. Dozias, F. Brulé-Morabito, J. Golda, C. Douat
Plasma Processes and Polymers (2023) - The cold atmospheric pressure plasma-generated species superoxide, singlet oxygen, and atomic oxygen activate the molecular chaperone Hsp33
T. Dirks, M. Krewing, K. Vogel, J. E. Bandow
Journal of the Royal Society Interface 20:20230300 (2023)
Repository: https://rdpcidat.rub.de/node/784 - Immobilization protects enzymes from plasma-mediated inactivation
T. Dirks, A. Yayci, S. Klopsch, M. Krewing, W. Zhang, F. Hollmann, J. E. Bandow
Journal of the Royal Society Interface 20:20230299 (2023)
Repository: https://rdpcidat.rub.de/node/763 - State enhanced actinometry in the COST microplasma jet
D Steuer, H van Impel, A R Gibson, V Schulz-von der Gathen, M Böke, J Golda
Plasma Sources Sci. Technol. 31, 10LT01 (2022) - RF-driven atmospheric-pressure capillary plasma jet in a He/O2 gas mixture: Multi-diagnostic approach to energy transport
T Winzer, D Steuer, S Schüttler, N Blosczyk, J Benedikt, J Golda
Journal of Applied Physics 132, 183301 (2022)
Thesis
- Emanuel Jeß, Bachelor thesis - 03/2021
Diagnostics of plasma-produced hydrogen peroxide in liquids - Steffen Schüttler, PhD thesis - ongoing
Energy transport in atmospheric pressure plasmas interacting with fluids - Maike Kai, Master thesis - 04/2023
Diagnostics of plasma chemistry in atmospheric pressure plasmas operated in humid feed gas - Océane Michels, Bachelor thesis - 10/2022
Undisclosed title - Lara Boeddinghaus, Bachelor thesis - 03/2023
Diagnostic of excitation dynamics in an atmospheric pressure plasma jet using phase resolved optical emission spectroscopy - Anna Lena Schöne, PhD thesis - ongoing
Simulation of plasma and liquid chemistry for applications in biocatalysis - Jannis Kaufmann, Bachelor thesis - 09/2023
Diagnostik von plasmaerzeugten Stickstoff- und Sauerstoffspezies in Flüssigkeiten - Sabrina Klopsch, PhD thesis - ongoing
- Niklas Eichstaedt, Bachelor thesis - 04/2024
Investigation of the influence of the excitation frequency on the production of plasma-generated hydrogen peroxide